Répertoire du corps professoral
Chantal Guillemette
Professeure titulaire
(418) 654-2296
Chantal.Guillemette@pha.ulaval.ca
Université Laval, Pavillon CHUL
2705, boul Laurier
Local R-4701.5
Investigate novel markers of kidney injury in children requiring a cardiac surgery
Organisme(s) subventionnaire(s): Harvard University
Type de financement: Subvention
Établissement tête: Harvard University
Du 20 décembre 2023
au19 décembre 2024
Association of Sex Steroid Hormones and Gallbladder Cancer in Women
Organisme(s) subventionnaire(s): National Institute of Health (USA)
Type de financement: Contrat
Établissement tête: Université Laval
Du 29 septembre 2023
au28 mars 2025
Projet portant sur les hormones stéroïdiennes et le cancer de la prostate
Organisme(s) subventionnaire(s): Fondation du CHU de Québec
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 septembre 2023
au31 août 2027
Targeting sex steroids to improve the response to bladder cancer immunotherapy
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 octobre 2021
au30 septembre 2026
Chaire de recherche du Canada en pharmacogénomique
Programme: Chaires de recherche du Canada - Fonctionnement
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 octobre 2020
au30 septembre 2027
Functional pharmacogenomics of cancer : from mechanisms to personalized therapy
Programme: Subventions Fondation
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 juillet 2019
au30 juin 2026
Effect of environmental contaminants and methylome of breast adipose tissue on aromatase inhibitor efficacy in breast cancer
Programme: Volet Projet: Concours pilotes
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 juillet 2016
au30 septembre 2024
Financements des 2 dernières années
Deep phenotyping of UGT human knockouts
Programme: Subvention Catalyseur : Analyse des données de l’Étude longitudinale canadienne sur le vieillissement
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 mars 2023
au29 février 2024
Understanding the variations in clinical presentations of endometriosis: a pan-Canadian cohort study
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 mars 2023
au29 février 2024
Une infrastructure IA multi-usagers clé en main pour gérer le cycle de vie complet des données en santé
Programme: BDR - Cas spéciaux et obligations institutionnelles
Organisme(s) subventionnaire(s): Université Laval - Fonds internes
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2021
au30 juin 2024
Encadrements terminés dans les 5 dernières années
Publications des 5 dernières années
Supplementary Table S2 from Prediagnostic Hormone Levels and Risk of Testicular Germ Cell Tumors: A Nested Case–Control Study in the Janus Serum Bank 2023/11/01. Zeni Wu, Britton Trabert, Chantal Guillemette, Patrick Caron, Gary Bradwin, Barry I. Graubard, Elisabete Weiderpass, Giske Ursin, Hilde Langseth, Katherine A. McGlynn. DOI 10.1158/1055-9965.24473808.v1
Supplementary Table S2 from Prediagnostic Hormone Levels and Risk of Testicular Germ Cell Tumors: A Nested Case–Control Study in the Janus Serum Bank 2023/11/01. Zeni Wu, Britton Trabert, Chantal Guillemette, Patrick Caron, Gary Bradwin, Barry I. Graubard, Elisabete Weiderpass, Giske Ursin, Hilde Langseth, Katherine A. McGlynn. DOI 10.1158/1055-9965.24473808
Supplementary Table S1 from Prediagnostic Hormone Levels and Risk of Testicular Germ Cell Tumors: A Nested Case–Control Study in the Janus Serum Bank 2023/11/01. Zeni Wu, Britton Trabert, Chantal Guillemette, Patrick Caron, Gary Bradwin, Barry I. Graubard, Elisabete Weiderpass, Giske Ursin, Hilde Langseth, Katherine A. McGlynn. DOI 10.1158/1055-9965.24473811
Supplementary Table S1 from Prediagnostic Hormone Levels and Risk of Testicular Germ Cell Tumors: A Nested Case–Control Study in the Janus Serum Bank 2023/11/01. Zeni Wu, Britton Trabert, Chantal Guillemette, Patrick Caron, Gary Bradwin, Barry I. Graubard, Elisabete Weiderpass, Giske Ursin, Hilde Langseth, Katherine A. McGlynn. DOI 10.1158/1055-9965.24473811.v1
Prediagnostic Hormone Levels and Risk of Testicular Germ Cell Tumors: A Nested Case–Control Study in the Janus Serum Bank Cancer Epidemiology, Biomarkers & Prevention, 2023/11/01. Zeni Wu, Britton Trabert, Chantal Guillemette, Patrick Caron, Gary Bradwin, Barry I. Graubard, Elisabete Weiderpass, Giske Ursin, Hilde Langseth, Katherine A. McGlynn. DOI 10.1158/1055-9965.EPI-23-0772
Data from Prediagnostic Hormone Levels and Risk of Testicular Germ Cell Tumors: A Nested Case–Control Study in the Janus Serum Bank 2023/11/01. Zeni Wu, Britton Trabert, Chantal Guillemette, Patrick Caron, Gary Bradwin, Barry I. Graubard, Elisabete Weiderpass, Giske Ursin, Hilde Langseth, Katherine A. McGlynn. DOI 10.1158/1055-9965.c.6908391
Data from Prediagnostic Hormone Levels and Risk of Testicular Germ Cell Tumors: A Nested Case–Control Study in the Janus Serum Bank 2023/11/01. Zeni Wu, Britton Trabert, Chantal Guillemette, Patrick Caron, Gary Bradwin, Barry I. Graubard, Elisabete Weiderpass, Giske Ursin, Hilde Langseth, Katherine A. McGlynn. DOI 10.1158/1055-9965.c.6908391.v1
Endogenous sex steroid hormones and risk of liver cancer among US men: Results from the Liver Cancer Pooling Project JHEP Reports, 2023/07. Zeni Wu, Jessica L. Petrick, Andrea A. Florio, Chantal Guillemette, Laura E. Beane Freeman, Julie E. Buring, Gary Bradwin, Patrick Caron, Yu Chen, A. Heather Eliassen, Lawrence S. Engel, Neal D. Freedman, J. Michael Gaziano, Edward L. Giovannuci, Jonathan N. Hofmann, Wen-Yi Huang, Victoria A. Kirsh, Cari M. Kitahara, Jill Koshiol, I-Min Lee, Linda M. Liao, Christina C. Newton, Julie R. Palmer, Mark P. Purdue, Thomas E. Rohan, Lynn Rosenberg, Howard D. Sesso, Rashmi Sinha, Meir J. Stampfer, Caroline Y. Um, Stephen K. Van Den Eeden, Kala Visvanathan, Jean Wactawski-Wende, Anne Zeleniuch-Jacquotte, Xuehong Zhang, Barry I. Graubard, Peter T. Campbell, Katherine A. McGlynn. DOI 10.1016/j.jhepr.2023.100742
A Non-Canonical Role for the Glycosyltransferase Enzyme UGT2B17 as a Novel Constituent of the B Cell Receptor Signalosome Cells, 2023/05. Antoine Wagner, Michèle Rouleau, Lyne Villeneuve, Trang Le, Cheryl Peltier, Éric P. Allain, Caroline Beaudoin, Sophie Tremblay, Fréderic Courtier, Flora Nguyen Van Long, Isabelle Laverdière, Éric Lévesque, Versha Banerji, Katrina Vanura, Chantal Guillemette. DOI 10.3390/cells12091295
Preoperative Circulating 11-Oxygenated Androgens Are Associated With Metastasis-free Survival in Localized Prostate Cancer Journal of Urology, 2023/02. Cylia Dahmani, Patrick Caron, David Simonyan, Louis Lacombe, Armen Aprikian, Fred Saad, Michel Carmel, Simone Chevalier, Eric Lévesque, Chantal Guillemette. DOI 10.1097/JU.0000000000003049
The Glycosyltransferase Pathway: An Integrated Analysis of the Cell Metabolome Metabolites, 2022/10/21. Yannick Audet-Delage, Michèle Rouleau, Lyne Villeneuve, Chantal Guillemette. DOI 10.3390/metabo12101006
A liquid chromatography-mass spectrometry assay for the quantification of nucleotide sugars in human plasma and urine specimens and its clinical application Journal of Chromatography A, 2022/08. Patrick Caron, Flora Nguyen Van Long, Michèle Rouleau, Emmanuel Bujold, Paul Fortin, Siamak Mohammadi, Éric Lévesque, Sylvie Breton, Chantal Guillemette. DOI 10.1016/j.chroma.2022.463296
A quantitative analysis of total and free 11-oxygenated androgens and its application to human serum and plasma specimens using liquid-chromatography tandem mass spectrometry Journal of Chromatography A, 2021/08. Patrick Caron, Véronique Turcotte, Chantal Guillemette. DOI 10.1016/j.chroma.2021.462228
Rationale for the combination of venetoclax and ibrutinib in T-prolymphocytic leukemia. Haematologica, 2021/08/01. DOI 10.3324/haematol.2020.271304
Follicle-stimulating hormone (FSH) levels prior to prostatectomy are not related to long-term oncologic or cardiovascular outcomes for men with prostate cancer. Asian journal of andrology, 2021/07/09. DOI 10.4103/aja.aja_58_21
Urinary oestrogen steroidome as an indicator of the risk of localised prostate cancer progression. British journal of cancer, 2021/04/07. DOI 10.1038/s41416-021-01376-z
IL15RA and SMAD3 Genetic Variants Predict Overall Survival in Metastatic Colorectal Cancer Patients Treated with FOLFIRI Therapy: A New Paradigm. Cancers, 2021/04/03. DOI 10.3390/cancers13071705
KLF5 and NFYA factors as novel regulators of prostate cancer cell metabolism. Endocrine-related cancer, 2021/04/01. DOI 10.1530/erc-20-0504
Circulating Levels of Sex Steroid Hormones and Gastric Cancer. Archives of medical research, 2021/03/27. DOI 10.1016/j.arcmed.2021.03.001
Associations Between Prediagnostic Concentrations of Circulating Sex Steroid Hormones and Liver Cancer Among Postmenopausal Women. Hepatology (Baltimore, Md.), 2020/08/01. DOI 10.1002/hep.31057
Reply to Comment on "UGT2B17 modifies drug response in chronic lymphocytic leukaemia". British journal of cancer, 2020/07/24. DOI 10.1038/s41416-020-1006-4
UGT2B17 modifies drug response in chronic lymphocytic leukaemia. British journal of cancer, 2020/05/18. DOI 10.1038/s41416-020-0887-6
Extragonadal Steroids Contribute Significantly to Androgen Receptor Activity and Development of Castration Resistance in Recurrent Prostate Cancer after Primary Therapy. The Journal of urology, 2020/05/01. DOI 10.1097/ju.0000000000000699
DNA repair gene polymorphisms, tumor control, and treatment toxicity in prostate cancer patients treated with permanent implant prostate brachytherapy. The Prostate, 2020/03/23. DOI 10.1002/pros.23975
Endogenous estradiol and inflammation biomarkers: potential interacting mechanisms of obesity-related disease. Cancer causes & control : CCC, 2020/02/25. DOI 10.1007/s10552-020-01280-6
Emerging roles for UDP-glucuronosyltransferases in drug resistance and cancer progression. British journal of cancer, 2020/02/12. DOI 10.1038/s41416-019-0722-0
Alternative promoters control UGT2B17-dependent androgen catabolism in prostate cancer and its influence on progression. British journal of cancer, 2020/02/12. DOI 10.1038/s41416-020-0749-2
Glucuronidation of Abiraterone and Its Pharmacologically Active Metabolites by UGT1A4, Influence of Polymorphic Variants and Their Potential as Inhibitors of Steroid Glucuronidation. Drug metabolism and disposition: the biological fate of chemicals, 2019/11/14. DOI 10.1124/dmd.119.088229
Inactivation of Prostaglandin E<inf>2</inf> as a Mechanism for UGT2B17-Mediated Adverse Effects in Chronic Lymphocytic Leukemia Frontiers in Oncology, 2019. Allain, E.P., Rouleau, M., Le, T., Vanura, K., Villeneuve, L., Caron, P., Turcotte, V., Lévesque, E., Guillemette, C.. DOI 10.3389/fonc.2019.00606
Germline variability and tumor expression level of ribosomal protein gene RPL28 are associated with survival of metastatic colorectal cancer patients Scientific Reports, 2019. Labriet, A., Lévesque, É., Cecchin, E., De Mattia, E., Villeneuve, L., Rouleau, M., Jonker, D., Couture, F., Simonyan, D., Allain, E.P., Buonadonna, A., D’Andrea, M., Toffoli, G., Guillemette, C.. DOI 10.1038/s41598-019-49477-3
Germline Polymorphisms in the Nuclear Receptors PXR and VDR as Novel Prognostic Markers in Metastatic Colorectal Cancer Patients Treated With FOLFIRI Frontiers in Oncology, 2019. De Mattia, E., Polesel, J., Roncato, R., Labriet, A., Bignucolo, A., Dreussi, E., Romanato, L., Guardascione, M., Buonadonna, A., D'Andrea, M., Lévesque, E., Jonker, D., Couture, F., Guillemette, C., Cecchin, E., Toffoli, G.. DOI 10.3389/fonc.2019.01312
Factors affecting interindividual variability of hepatic UGT2B17 protein expression examined using a novel specific monoclonal antibody <sup>S</sup> Drug Metabolism and Disposition, 2019. Émond, J.-P., Labriet, A., Desjardins, S., Rouleau, M., Villeneuve, L., Hovington, H., Brisson, H., Lacombe, L., Simonyan, D., Caron, P., Périgny, M., Têtu, B., Fallon, J.K., Klein, K., Smith, P.C., Zanger, U.M., Guillemette, C., Lévesque, E.. DOI 10.1124/dmd.119.086330
Discordance between testosterone measurement methods in castrated prostate cancer patients Endocrine Connections, 2019. Rouleau, M., Lemire, F., Déry, M., Thériault, B., Dubois, G., Fradet, Y., Toren, P., Guillemette, C., Lacombe, L., Klotz, L., Saad, F., Guérette, D., Pouliot, F.. DOI 10.1530/EC-18-0476
Combination of germline variations associated with survival of folinic acid, fluorouracil and irinotecan-treated metastatic colorectal cancer patients Pharmacogenomics, 2019. Labriet, A., Lévesque, É., De Mattia, E., Cecchin, E., Jonker, D., Couture, F., Simonyan, D., Buonadonna, A., D'andrea, M., Villeneuve, L., Toffoli, G., Guillemette, C.. DOI 10.2217/pgs-2019-0091
Associations between prediagnostic concentrations of circulating sex steroid hormones and esophageal/gastric cardia adenocarcinoma among men Journal of the National Cancer Institute, 2019. Petrick, J.L., Hyland, P.L., Caron, P., Falk, R.T., Pfeiffer, R.M., Dawsey, S.M., Abnet, C.C., Taylor, P.R., Weinstein, S.J., Albanes, D., Freedman, N.D., Gapstur, S.M., Bradwin, G., Guillemette, C., Campbell, P.T., Cook, M.B.. DOI 10.1093/jnci/djy082
A comprehensive analysis of steroid hormones and progression of localized high-risk prostate cancer Cancer Epidemiology Biomarkers and Prevention, 2019. Levesque, E., Caron, P., Lacombe, L., Turcotte, V., Simonyan, D., Fradet, Y., Aprikian, A., Saad, F., Carmel, M., Chevalier, S., Guillemette, C.. DOI 10.1158/1055-9965.EPI-18-1002
An LC-MS/MS method for quantification of abiraterone, its active metabolites D(4)-abiraterone (D4A) and 5α-abiraterone, and their inactive glucuronide derivatives Journal of Chromatography B, 2019/01. Patrick Caron, Véronique Turcotte, Eric Lévesque, Chantal Guillemette. DOI 10.1016/j.jchromb.2018.12.003
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