Répertoire du corps professoral

Investigation of neuroprotective and neurorescue properties of zuranolone in a mouse model of Parkinson’s disease
Programme: Programme de projets pilotes
Organisme(s) subventionnaire(s): Parkinson Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 août 2024 au 31 juillet 2025

Mechanisms of action of sex-specific endocrine treatments in complementary models of Parkinson's disease
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2024 au 31 mars 2029

Financements des 2 dernières années

Mechanisms of action of sex-specific endocrine treatments in animal models of Parkinson's disease
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 mars 2023 au 29 février 2024

Étude préclinique et pharmacoépidémiologique de l’impact du dutastéride dans l’étiopathogenèse et la progression de la maladie de Parkinson
Programme: Réseaux thématiques de recherche
Organisme(s) subventionnaire(s): Fonds de recherche du Québec - Santé
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2021 au 31 août 2023

Sex-specific investigations of Parkinson's disease mouse models: application for gonadal drugs repurposing
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 octobre 2018 au 31 mars 2023

Encadrements terminés dans les 5 dernières années

Solène Pradeloux, Maîtrise en sciences pharmaceutiques - avec mémoire

Amandine Isenbrandt, Maîtrise en sciences pharmaceutiques - avec mémoire

Jérôme Lamontagne-Proulx, Doctorat en sciences pharmaceutiques

Publications des 5 dernières années

Oral Trehalose Intake Modulates the Microbiota–Gut–Brain Axis and Is Neuroprotective in a Synucleinopathy Mouse Model Nutrients, 2024/09/30. Solène Pradeloux, Katherine Coulombe, Alexandre Jules Kennang Ouamba, Amandine Isenbrandt, Frédéric Calon, Denis Roy, Denis Soulet. DOI 10.3390/nu16193309

Sex and Age Differences in a Progressive Synucleinopathy Mouse Model Biomolecules, 2023/06/11. Jérôme Lamontagne-Proulx, Katherine Coulombe, Marc Morissette, Marie Rieux, Frédéric Calon, Thérèse Di Paolo, Denis Soulet. DOI 10.3390/biom13060977

Impact of Sex on Neuroimmune contributions to Parkinson's disease. Brain research bulletin, 2023/05/15. Bourque M, Morissette M, Soulet D, Di Paolo T. DOI 10.1016/j.brainresbull.2023.110668

Three-Dimensional Analysis of Sex- and Gonadal Status- Dependent Microglial Activation in a Mouse Model of Parkinson's Disease. Pharmaceuticals (Basel, Switzerland), 2023/01/20. Isenbrandt A, Coulombe K, Morissette M, Bourque M, Jérôme Lamontagne-Proulx, Di Paolo T, Soulet D. DOI 10.3390/ph16020152

Peripheral Neuroprotective and Immunomodulatory Effects of 5α-Reductase Inhibitors in Parkinson's Disease Models. Frontiers in pharmacology, 2022/07/22. Poirier AA, Côté M, Jarras H, Litim N, Lamontagne-Proulx J, Al-Sweidi S, Morissette M, Lachhab A, Pelletier M, Thérèse Di Paolo, Soulet D. DOI 10.3389/fphar.2022.898067

Differential contribution of estrogen receptors to the intestinal therapeutic effects of 17β-estradiol in a murine model of Parkinson's disease. Brain research bulletin, 2022/07/01. Poirier AA, Côté M, Bourque M, Jarras H, Lamontagne-Proulx J, Morissette M, Paolo TD, Soulet D. DOI 10.1016/j.brainresbull.2022.06.019

Live imaging of platelets and neutrophils during antibody-mediated neurovascular thrombosis Blood Advances, 2022/06/28. Audree Laroche, Denis Soulet, Marc Bazin, Tania Levesque, Isabelle Allaeys, Nicolas Vallières, Matthias Gunzer, Louis Flamand, Steve Lacroix, Eric Boilard. DOI 10.1182/bloodadvances.2021006728

A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease. PLoS biology, 2022/03/09. DOI 10.1371/journal.pbio.3001578

Androgens and Parkinson's Disease: A Review of Human Studies and Animal Models. Androgens: clinical research and therapeutics, 2021/12/23. DOI 10.1089/andro.2021.0011

Effect of Docosahexaenoic Acid (DHA) at the Enteric Level in a Synucleinopathy Mouse Model. Nutrients, 2021/11/24. DOI 10.3390/nu13124218

Effect of sex and gonadectomy on brain MPTP toxicity and response to dutasteride treatment in mice. Neuropharmacology, 2021/09/20. DOI 10.1016/j.neuropharm.2021.108784

Ovine model of congenital chest wall and spine deformity with alterations of respiratory mechanics: follow-up from birth to three months. Studies in health technology and informatics, 2021/06/01. DOI 10.3233/shti210485

Platelets release mitochondrial antigens in systemic lupus erythematosus. Science translational medicine, 2021/02/01. DOI 10.1126/scitranslmed.aav5928

Hedgehog signaling pathway regulates gene expression profile of epididymal principal cells through the primary cilium. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020/04/13. DOI 10.1096/fj.202000328r

Multiphoton intravital microscopy in small animals: motion artefact challenges and technical solutions Journal of Microscopy, 2020/04. D. SOULET, J. LAMONTAGNE‐PROULX, B. AUBÉ, D. DAVALOS. DOI 10.1111/jmi.12880

Neuroprotection and immunomodulation in the gut of parkinsonian mice with a plasmalogen precursor. Brain research, 2019/09/13. DOI 10.1016/j.brainres.2019.146460

Neuroprotection and immunomodulation of progesterone in the gut of a mouse model of Parkinson's disease. Journal of neuroendocrinology, 2019/09/10. DOI 10.1111/jne.12782

Revisiting structure/functions of the human epididymis. Andrology, 2019/04/29. DOI 10.1111/andr.12633