Répertoire du corps professoral

Global signals in dendrites of GABAergic inhibitory interneurons : mechanisms and function
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 octobre 2022 au 30 septembre 2027

Dendritic inhibition in hippocampal circuits
Programme: Subventions à la découverte SD (individuelles et d'équipe)
Organisme(s) subventionnaire(s): Conseil de recherches en sciences naturelles et génie Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2020 au 31 mars 2025

Financements des 2 dernières années

Imagerie et interrogation des circuits cérébraux chez les animaux en comportement
Programme: Fonds des leaders John-R.-Evans (FLJR)
Organisme(s) subventionnaire(s): Ministère de l'Économie et de l'Innovation, Fondation Canadienne pour l'innovation (La)
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 février 2023 au 24 mai 2024

Inhibitory control of hippocampal inhibitory circuits: cell types, neuromodulation and function
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 octobre 2019 au 30 septembre 2024

Investigating the contribution of Shank3 in Alzheimer's disease
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2018 au 31 mars 2023

Encadrements terminés dans les 5 dernières années

Félix Michaud, Maîtrise en biochimie - avec mémoire

Sona Amalyan, Doctorat en biochimie

Publications des 5 dernières années

Altered firing output of VIP interneurons and early dysfunctions in CA1 hippocampal circuits in the 3xTg mouse model of Alzheimer’s disease eLife, 2024/09/12. Felix Michaud, Ruggiero Francavilla, Dimitry Topolnik, Parisa Iloun, Suhel Tamboli, Frederic Calon, Lisa Topolnik. DOI 10.7554/elife.95412

Mouse hippocampal CA1 VIP interneurons detect novelty in the environment and support recognition memory Cell Reports, 2024/04. Suhel Tamboli, Sanjay Singh, Dimitry Topolnik, Mohamed El Amine Barkat, Risna Radhakrishnan, Alexandre Guet-McCreight, Lisa Topolnik. DOI 10.1016/j.celrep.2024.114115

Editorial: GABAergic circuits in health and disease Frontiers in Neural Circuits, 2023/10/31. Lisa Topolnik, Graziella Di Cristo, Elsa Rossignol. DOI 10.3389/fncir.2023.1322193

Inhibitory circuits in fear memory and fear-related disorders Frontiers in Neural Circuits, 2023/03/23. Sanjay Singh, Lisa Topolnik. DOI 10.3389/fncir.2023.1122314

Enhanced motor cortex output and disinhibition in asymptomatic female mice with C9orf72 genetic expansion Cell Reports, 2022/07. Sona Amalyan, Suhel Tamboli, Ivan Lazarevich, Dimitry Topolnik, Leandra Harriet Bouman, Lisa Topolnik. DOI 10.1016/j.celrep.2022.111043

The role of inhibitory circuits in hippocampal memory processing Nature Reviews Neuroscience, 2022/05. Lisa Topolnik, Suhel Tamboli. DOI 10.1038/s41583-022-00599-0

Cholinergic Modulation of Dendritic Signaling in Hippocampal GABAergic Inhibitory Interneurons Neuroscience, 2022/05. Luca Pancotti, Lisa Topolnik. DOI 10.1016/j.neuroscience.2021.06.011

Spring Hippocampal Research Conference and Beyond Frontiers Research Topics, 2022. DOI 10.3389/978-2-88971-814-6

Editorial: Spring Hippocampal Research Conference and Beyond Frontiers in Molecular Neuroscience, 2021/10. James A. Ainge, Mariangela Chisari, Akiva Cohen, Steven J. Mennerick, Lisa Topolnik, Jochen C. Meier. DOI 10.3389/fnmol.2021.773308

Cortical disinhibitory circuits: cell types, connectivity and function Trends in Neurosciences, 2021/08. Klas Kullander, Lisa Topolnik. DOI 10.1016/j.tins.2021.04.009

Structural analysis of the microglia–interneuron interactions in the CA1 hippocampal area of the APP/PS1 mouse model of Alzheimer's disease Journal of Comparative Neurology, 2021. Étienne Gervais, Parisa Iloun, Ekaterina Martianova, Ana Claudia Gonçalves Bessa, Serge Rivest, Lisa Topolnik. DOI 10.1002/cne.25289

Sex Differences of Microglia and Synapses in the Hippocampal Dentate Gyrus of Adult Mouse Offspring Exposed to Maternal Immune Activation Frontiers in Cellular Neuroscience, 2020/10. Chin Wai Hui, Haley A. Vecchiarelli, Étienne Gervais, Xiao Luo, Félix Michaud, Lisa Scheefhals, Kanchan Bisht, Kaushik Sharma, Lisa Topolnik, Marie-Ève Tremblay. DOI 10.3389/fncel.2020.558181

Alterations in Intrinsic and Synaptic Properties of Hippocampal CA1 VIP Interneurons During Aging Frontiers in Cellular Neuroscience, 2020/10. Ruggiero Francavilla, Alexandre Guet-McCreight, Sona Amalyan, Chin Wai Hui, Dimitry Topolnik, Félix Michaud, Beatrice Marino, Marie-Ève Tremblay, Frances K. Skinner, Lisa Topolnik. DOI 10.3389/fncel.2020.554405

Common Principles in Functional Organization of VIP/Calretinin Cell-Driven Disinhibitory Circuits Across Cortical Areas Frontiers in Neural Circuits, 2020/06/09. Alexandre Guet-McCreight, Frances K. Skinner, Lisa Topolnik. DOI 10.3389/fncir.2020.00032

Corrigendum: Synaptic Mechanisms Underlying the Network State-Dependent Recruitment of VIP-Expressing Interneurons in the CA1 Hippocampus Cerebral Cortex, 2020/04/06. Xiao Luo, Alexandre Guet-McCreight, Vincent Villette, Ruggiero Francavilla, Beatrice Marino, Simon Chamberland, Frances K Skinner, Lisa Topolnik. DOI 10.1093/cercor/bhaa094

Synaptic Mechanisms Underlying the Network State-Dependent Recruitment of VIP-Expressing Interneurons in the CA1 Hippocampus Cerebral Cortex, 2020/02. Xiao Luo, Alexandre Guet-McCreight, Vincent Villette, Ruggiero Francavilla, Beatrice Marino, Simon Chamberland, Frances K Skinner, Lisa Topolnik. DOI 10.1093/cercor/bhz334

Transcriptomic profile of the subiculum-projecting VIP GABAergic neurons in the mouse CA1 hippocampus Brain Structure and Function, 2019/05. Xiao Luo, Einer Muñoz-Pino, Ruggiero Francavilla, Maxime Vallée, Arnaud Droit, Lisa Topolnik. DOI 10.1007/s00429-019-01883-z

Calcium Dynamics in Dendrites of Hippocampal CA1 Interneurons in Awake Mice Frontiers in Cellular Neuroscience, 2019/03. Ruggiero Francavilla, Vincent Villette, Olivier Martel, Lisa Topolnik. DOI 10.3389/fncel.2019.00098

Non-linear calcium signalling and synaptic plasticity in interneurons Current Opinion in Neurobiology, 2019/02. Lisa Topolnik, Olivier Camiré. DOI 10.1016/j.conb.2018.09.006

Calcium extrusion mechanisms in dendrites of mouse hippocampal CA1 inhibitory interneurons Cell Calcium, 2019/01. Simon Chamberland, Alfonsa Zamora Moratalla, Lisa Topolnik. DOI 10.1016/j.ceca.2018.12.002