Répertoire du corps professoral
Pierre Marquet
Médecin clinicien enseignant titulaire
Pierre.Marquet@neuro.ulaval.ca
Pavillon Ferdinand-Vandry
1050, avenue de la Médecine
Local 4873
Centre d'optique, photonique et lasers
Programme: Regroupements stratégiques NT
Organisme(s) subventionnaire(s): École polytechnique de Montréal, Université du Québec à Trois-Rivières, École de technologie supérieure, Université de Sherbrooke, Université Concordia, Université Laval - Fonds internes, Institut national de recherche scientifique (INRS), Fonds de recherche du Québec - Nature et technologies, Université McGill
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2024
au 31 mars 2030
Development of a methodology based on digital holographic microscopy to study cell homeostasis by measuring cell volume dynamics and water fluxes
Programme: Subventions à la découverte SD (individuelles et d'équipe)
Organisme(s) subventionnaire(s): Conseil de recherches en sciences naturelles et génie Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2024
au 31 mars 2029
Repousser les frontières de l'étude de la biologie à l'échelle nanométrique en conditions naturelles
Programme: Fonds d'innovation (FI)
Organisme(s) subventionnaire(s): Fondation Canadienne pour l'innovation (La), CIUSSS-CN CERVO, Ministère de l'Économie et de l'Innovation et de l'énergie, Ministère de la Santé et des Services sociaux
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 juillet 2023
au 31 mars 2025
Unité mixte internationale (UMI) en neuro-développement et psychiatrie de l’enfant
Programme: BDR - Contributions
Organisme(s) subventionnaire(s): Université Laval - Fonds internes
Type de financement: Subvention
Établissement tête: Université Laval
Du 17 mai 2023
au 31 mars 2030
Développement d'un imageur pour diagnostiquer les troubles de l'humeur aux points de services
Programme: Sentinelle Nord - Fonds de maturation
Organisme(s) subventionnaire(s): Secrétariat des programmes interorganismes à l’intention des établissements
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 mai 2023
au 30 avril 2025
Télé-NEUROS (Nouvel Environnement Universitaire de Recherche Orchestrée en Santé mentale et cognitive: une télé initiative)
Organisme(s) subventionnaire(s): CIUSSS-CN CERVO, CIUSSS-CN Centre interdisciplinaire de recherche en réadaptation et intégration sociale (CIRRIS), Université Laval - Fonds internes
Type de financement: Subvention
Établissement tête: Université Laval
Du 20 octobre 2020
au 31 mars 2026
Financements des 2 dernières années
Repetitive transcranial magnetic stimulation to prevent mental health disorders
Programme: Nouvelles frontières en recherche
Organisme(s) subventionnaire(s): Secrétariat des programmes interorganismes à l’intention des établissements
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 mars 2022
au 28 février 2025
Unveiling comprehensive cellular biophysical properties using quantitative phase digital holographic microscopy
Programme: Subventions à la découverte SD (individuelles et d'équipe)
Organisme(s) subventionnaire(s): Secrétariat Inter-Conseils (Canada) (CRSH, CRSNG, IRSC), Conseil de recherches en sciences naturelles et génie Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2018
au 31 mars 2024
Centre d'optique photonique et laser (COPL)
Programme: Regroupements stratégiques NT
Organisme(s) subventionnaire(s): Université de Sherbrooke, École polytechnique de Montréal, Université McGill, Université Concordia, Fonds de recherche du Québec - Nature et technologies, École de technologie supérieure, Université Laval - Fonds internes
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2017
au 31 mars 2024
Smart, adaptative, and autonomous sensing
Programme: Programme de formation orientée vers la nouveauté, la collaboration et l'expérience en recherche (FONCER)
Organisme(s) subventionnaire(s): Université Laval - Fonds internes, Secrétariat Inter-Conseils (Canada) (CRSH, CRSNG, IRSC), Sentinelle Nord, Conseil de recherches en sciences naturelles et génie Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2017
au 31 mars 2024
Support de Sentinelle Nord à l'Unité mixte internationale en psychiatrie et neurodéveloppement
Programme: Fonds d'excellence en recherche Apogée Canada
Organisme(s) subventionnaire(s): Secrétariat des programmes interorganismes à l’intention des établissements
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 septembre 2015
au 31 mars 2023
Chaire d'excellence en recherche du Canada en neurophotonique
Programme: Programme de chaires d'excellence en recherche du Canada
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada, Université Laval - Fonds internes
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 janvier 2015
au 31 décembre 2023
Encadrements terminés dans les 5 dernières années
Publications des 5 dernières années
To be or not to be, when synthetic data meet clinical pharmacology: A focused study on pharmacogenetics CPT: Pharmacometrics & Systems Pharmacology, 2025/01. Jean‐Baptiste Woillard, Clément Benoist, Alexandre Destere, Marc Labriffe, Giulia Marchello, Julie Josse, Pierre Marquet. DOI 10.1002/psp4.13240
Killing several birds with one stone: A multi‐indication population pharmacokinetic model and Bayesian estimator for enteric‐coated mycophenolate sodium British Journal of Clinical Pharmacology, 2024/12/22. Yeleen Fromage, Hamza Sayadi, Kevin Koloskoff, Pierre Marquet, Marc Labriffe, Caroline Monchaud, Jean‐Baptiste Woillard. DOI 10.1111/bcp.16374
Revisiting the nature and pharmacodynamics of tacrolimus metabolites Pharmacological Research, 2024/11. Rudy Mevizou, Hassan Aouad, François-Ludovic Sauvage, Hélène Arnion, Emilie Pinault, Jean-Sébastien Bernard, Gildas Bertho, Nicolas Giraud, Rodolphe Alves de Sousa, Adolfo Lopez-Noriega, Florent Di Meo, Mélanie Campana, Pierre Marquet. DOI 10.1016/j.phrs.2024.107438
Proximal Tubule-on-Chip for Predicting Cation Transport: Dynamic Insights into Drug Transporter Expression and Function 2024/10/15. Isy Petit, Quentin Faucher, Jean-Sébastien Bernard, Perrine Giunchi, Antoine Humeau, François-Ludovic Sauvage, Pierre Marquet, Nicolas Védrenne, Florent Di Meo. DOI 10.1101/2024.10.12.617976
Application of machine-learning models to predict the ganciclovir and valganciclovir exposure in children using a limited sampling strategy Antimicrobial Agents and Chemotherapy, 2024/10/08. Laure Ponthier, Bénédicte Franck, Julie Autmizguine, Marc Labriffe, Philippe Ovetchkine, Pierre Marquet, Anders Åsberg, Jean-Baptiste Woillard. DOI 10.1128/aac.00860-24
Getting Tacrolimus Dosing Right Therapeutic Drug Monitoring, 2024/10/02. Pierre Marquet. DOI 10.1097/ftd.0000000000001266
Population Pharmacokinetics and Limited Sampling Strategy of Mycophenolate Mofetil for Indian Patients With Lupus Nephritis Therapeutic Drug Monitoring, 2024/10. Kévin KOLOSKOFF, Ritika Panwar, Manish Rathi, Sumith Mathew, Aman Sharma, Pierre Marquet, Sylvain Benito, Jean-Baptiste Woillard, Dr Smita Pattanaik. DOI 10.1097/ftd.0000000000001213
Everolimus Personalized Therapy: Second Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology Therapeutic Drug Monitoring, 2024/09/25. Satohiro Masuda, Florian Lemaitre, Markus J. Barten, Stein Bergan, Maria Shipkova, Teun van Gelder, Sander Vinks, Eberhard Wieland, Kirsten Bornemann-Kolatzki, Mercè Brunet, Brenda de Winter, Maja-Theresa Dieterlen, Laure Elens, Taihei Ito, Kamisha Johnson-Davis, Pawel K. Kunicki, Roland Lawson, Nuria Lloberas, Pierre Marquet, Olga Millan, Tomoyuki Mizuno, Dirk Jan A. R. Moes, Ofelia Noceti, Michael Oellerich, Smita Pattanaik, Tomasz Pawinski, Christoph Seger, Ron van Schaik, Raman Venkataramanan, Phil Walson, Jean-Baptiste Woillard, Loralie J. Langman. DOI 10.1097/ftd.0000000000001250
Identification of non-adherence to adjuvant letrozole using a population pharmacokinetics approach in hormone receptor-positive breast cancer patients European Journal of Pharmaceutical Sciences, 2024/08. Alicja Puszkiel, Florence Dalenc, Naïma Tafzi, Pierre Marquet, Marc Debled, William Jacot, Laurence Venat-Bouvet, Catherine Ferrer, Nadia Levasseur, Rodolphe Paulon, Jérôme Dauba, Alexandre Evrard, Vincent Mauriès, Thomas Filleron, Etienne Chatelut, Fabienne Thomas, Melanie White-Koning. DOI 10.1016/j.ejps.2024.106809
Gut microbiota biotransformation of drug glucuronides leading to gastrointestinal toxicity: Therapeutic potential of bacterial β-glucuronidase inhibition in mycophenolate-induced enteropathy Life Sciences, 2024/08. Clarisse Brossier, Manon Jardou, Angelika Janaszkiewicz, Djouher Firoud, Isy Petit, Hélène Arnion, Emilie Pinault, François-Ludovic Sauvage, Anne Druilhe, Nicolas Picard, Florent Di Meo, Pierre Marquet, Roland Lawson. DOI 10.1016/j.lfs.2024.122792
Better Rejection‐Free Survival at Three Years in Kidney Transplant Recipients With Model‐Informed Precision Dosing of Mycophenolate Mofetil Clinical Pharmacology & Therapeutics, 2024/08. Claire Villeneuve, Antoine Humeau, Caroline Monchaud, Marc Labriffe, Jean‐phillipe Rerolle, Lionel Couzi, Pierre‐François Westeel, Isabelle Etienne, Nassim Kamar, Mathias Büchler, Antoine Thierry, Pierre Marquet. DOI 10.1002/cpt.3206
A Machine Learning Algorithm to Predict the Starting Dose of Daptomycin Clinical Pharmacokinetics, 2024/08. Florence Rivals, Sylvain Goutelle, Cyrielle Codde, Romain Garreau, Laure Ponthier, Pierre Marquet, Tristan Ferry, Marc Labriffe, Alexandre Destere, Jean-Baptiste Woillard. DOI 10.1007/s40262-024-01405-z
The Cost-effectiveness of Valganciclovir Prophylaxis Versus Preemptive Therapy in CMV R+ Kidney Transplant Recipients Over the First Year Posttransplantation Transplantation Direct, 2024/07/26. Claire Villeneuve, Jean-Phillipe Rerolle, Lionel Couzi, Pierre-Francois Westeel, Isabelle Etienne, Laure Esposito, Nassim Kamar, Mathias Büchler, Antoine Thierry, Pierre Marquet, Caroline Monchaud. DOI 10.1097/TXD.0000000000001678
What is the best source for searching drug with CIP codes in the French health reimbursement data system (SNDS) database? Therapies, 2024/06. Sylvain Couderc, Sabrina Crépin, Marc Labriffe, Caroline Monchaud, Hélène Roussel, Alexandre Garnier, Aurélie Prémaud, Claire Villeneuve, Clément Benoist, Jean-Baptiste Woillard, Pierre Marquet. DOI 10.1016/j.therap.2024.05.001
In Silico Pharmacokinetics Evaluation of Forgiveness for Doravirine and Rilpivirine Therapeutic Drug Monitoring, 2024/06. Yeleen Fromage, Najwa Jamal, Cyrielle Codde, Caroline Monchaud, Marc Labriffe, Laure Ponthier, Pierre Marquet, Jean François Faucher, Jean-Baptiste Woillard. DOI 10.1097/ftd.0000000000001169
Activities of clinical pharmacologists across Europe: A survey by the European association of clinical pharmacology and therapeutics European Journal of Clinical Pharmacology, 2024/06. Pierre Marquet, Emilie Jouanjus, Joaquin Sáez-Peñataro, Aranzazu Sancho-Lopez. DOI 10.1007/s00228-024-03657-x
A machine learning approach to predict daptomycin exposure from two concentrations based on Monte Carlo simulations Antimicrobial Agents and Chemotherapy, 2024/05/02. Cyrielle Codde, Florence Rivals, Alexandre Destere, Yeleen Fromage, Marc Labriffe, Pierre Marquet, Clément Benoist, Laure Ponthier, Jean-François Faucher, Jean-Baptiste Woillard. DOI 10.1128/aac.01415-23
The Clinical Relevance of the Infiltrating Immune Cell Composition in Kidney Transplant Rejection Journal of the American Society of Nephrology, 2024/04/19. Thibaut Vaulet, Jasper Callemeyn, Baptiste Lamarthée, Asier Antoranz, Tim Debyser, Priyanka Joseph Koshy, Dany ANGLICHEAU, Jill Colpaert, Wilfried Gwinner, Philip Halloran, Dirk RJ Kuypers, Claire Tinel, Amaryllis Van Craenenbroeck, Elisabet Van Loon, Pierre Marquet, Francesca Maria Bosisio, Maarten Naesens. DOI 10.1681/asn.0000000000000350
Optimization of Ganciclovir and Valganciclovir Starting Dose in Children by Machine Learning Clinical Pharmacokinetics, 2024/04. Laure Ponthier, Julie Autmizguine, Benedicte Franck, Anders Åsberg, Philippe Ovetchkine, Alexandre Destere, Pierre Marquet, Marc Labriffe, Jean-Baptiste Woillard. DOI 10.1007/s40262-024-01362-7
Solid organ transplantation and gut microbiota: a review of the potential immunomodulatory properties of short-chain fatty acids in graft maintenance Frontiers in Cellular and Infection Microbiology, 2024/02/27. Manon Jardou, Clarisse Brossier, Pierre Marquet, Nicolas Picard, Anne Druilhe, Roland Lawson. DOI 10.3389/fcimb.2024.1342354
Early detection of liver injuries by the Serum enhanced binding test sensitive to albumin post-transcriptional modifications Scientific Reports, 2024/01/16. Souleiman El Balkhi, Mohamad Ali Rahali, Roy Lakis, François Ludovic Sauvage, Marving Martin, Angelika Janaszkiewicz, Roland Lawson, Ruben Goncalves, Paul Carrier, Veronique Loustaud-Ratti, Anne Guyot, Pierre Marquet, Florent Di Meo, Franck Saint-Marcoux. DOI 10.1038/s41598-024-51412-0
Absolute Quantification of Human Serum Albumin Isoforms by Internal Calibration Based on a Top-Down LC-MS Approach Analytical Chemistry, 2024/01/16. Roy Lakis, François-Ludovic Sauvage, Emilie Pinault, Pierre Marquet, Franck Saint-Marcoux, Souleiman El Balkhi. DOI 10.1021/acs.analchem.3c03933
Limited sampling strategy and population pharmacokinetic model of mycophenolic acid in pediatric patients with systemic lupus erythematosus: application of a double gamma absorption model with SAEM algorithm European Journal of Clinical Pharmacology, 2024/01. Kévin Koloskoff, Sylvain Benito, Lucie Chambon, Frédéric Dayan, Pierre Marquet, Evelyne Jacqz-Aigrain, Jean-Baptiste Woillard. DOI 10.1007/s00228-023-03587-0
Improvement of Charcot-Marie-Tooth Phenotype with a Nanocomplex Treatment in Two Transgenic Models of CMT1A Biomaterials Research, 2024/01. Mohamed El Massry, Zeina Msheik, Tarek El Masri, Gautier MA Ndong Ntoutoume, Laetitia Vignaud, Laurence Richard, Emilie Pinault, Pierre-Antoine Faye, Frédérique Bregier, Pierre Marquet, Frédéric Favreau, Jean-Michel Vallat, Fabrice Billet, Vincent Sol, Franck Sturtz, Alexis Desmouliere. DOI 10.34133/bmr.0009
Tacrolimus population pharmacokinetics in adult heart transplant patients British Journal of Clinical Pharmacology, 2023/12. Adrien Paschier, Alexandre Destere, Caroline Monchaud, Marc Labriffe, Pierre Marquet, Jean-Baptiste Woillard. DOI 10.1111/bcp.15857
Estimation of the prevalence of uterine infertility and its different causes in France according to data from a literature review Journal of Gynecology Obstetrics and Human Reproduction, 2023/12. E. Bouko-Levy, C. Vialaret, C. Sallée, P. Marquet, F. Margueritte, L. Dion, V. Lavoue, tristan gauthier. DOI 10.1016/j.jogoh.2023.102684
Within-subject pharmacokinetic variability has a strong influence on individual exposure ratios in bioequivalence studies, hence on drug formulation interchangeability European Journal of Clinical Pharmacology, 2023/11. Philippe Lechat, Fatma Kir, Pierre Marquet, Jean-Baptiste Woillard. DOI 10.1007/s00228-023-03565-6
Bridging the Worlds of Pharmacometrics and Machine Learning Clinical Pharmacokinetics, 2023/11. Kamilė Stankevičiūtė, Jean-Baptiste Woillard, Richard W. Peck, Pierre Marquet, Mihaela van der Schaar. DOI 10.1007/s40262-023-01310-x
Semi-synthetic human albumin isoforms: Production, structure, binding capacities and influence on a routine laboratory test International Journal of Biological Macromolecules, 2023/10. Roy Lakis, François-Ludovic Sauvage, Emilie Pinault, Pierre Marquet, Franck Saint-Marcoux, Souleiman El Balkhi. DOI 10.1016/j.ijbiomac.2023.126239
Impact of hypoxia and reoxygenation on the extra/intracellular metabolome and on transporter expression in a human kidney proximal tubular cell line Metabolomics, 2023/09/13. Quentin Faucher, Stéphanie Chadet, Antoine Humeau, François-Ludovic Sauvage, Hélène Arnion, Philippe Gatault, Matthias Buchler, Sébastien Roger, Roland Lawson, Pierre Marquet, Chantal Barin-Le Guellec. DOI 10.1007/s11306-023-02044-4
Tacrolimus Exposure Before and After a Switch From Twice-Daily Immediate-Release to Once-Daily Prolonged Release Tacrolimus: The ENVARSWITCH Study Transplant International, 2023/08/01. Caroline Monchaud, Jean-Baptiste Woillard, Sabrina Crépin, Naïma Tafzi, Ludovic Micallef, Jean-Philippe Rerolle, Sébastien Dharancy, Filomena Conti, Gabriel Choukroun, Antoine Thierry, Matthias Buchler, Ephrem Salamé, Cyril Garrouste, Christophe Duvoux, Charlotte Colosio, Pierre Merville, Dany Anglicheau, Isabelle Etienne, Faouzi Saliba, Christophe Mariat, Marilyne Debette-Gratien, Pierre Marquet. DOI 10.3389/ti.2023.11366
Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII+ innate immune cells in rejection Nature Communications, 2023/07/19. Baptiste Lamarthée, Jasper Callemeyn, Yannick Van Herck, Asier Antoranz, Dany ANGLICHEAU, Patrick Boada, Jan Ulrich Becker, Tim Debyser, Frederik De Smet, Katrien De Vusser, Maëva Eloudzeri, Amelie Franken, Wilfried Gwinner, Priyanka Joseph Koshy, Dirk Kuypers, Diether Lambrechts, Pierre Marquet, Virginie Mathias, Marion Rabant, Minnie M. Sarwal, Aleksandar Senev, Tara K. Sigdel, Ben Sprangers, Olivier Thaunat, Claire Tinel, Thomas Van Brussel, Amaryllis Van Craenenbroeck, Elisabet Van Loon, Thibaut Vaulet, Francesca Maria Bosisio, Maarten Naesens. DOI 10.1038/s41467-023-39859-7
Urinary collagen peptides: Source of markers for bone metabolic processes in kidney transplant recipients PROTEOMICS – Clinical Applications, 2023/07. David Marx, Dany Anglicheau, Sophie Caillard, Bruno Moulin, Audrey Kochman, Harald Mischak, Agnieszka Latosinska, Frank Bienaimé, Dominique Prié, Pierre Marquet, Peggy Perrin, Wilfried Gwinner, Jochen Metzger. DOI 10.1002/prca.202200118
A multi-omics investigation of tacrolimus off-target effects on a proximal tubule cell-line Pharmacological Research, 2023/06. Hassan Aouad, Quentin Faucher, François-Ludovic Sauvage, Emilie Pinault, Claire-Cécile Barrot, Hélène Arnion, Marie Essig, Pierre Marquet. DOI 10.1016/j.phrs.2023.106794
Active or passive maternal smoking increases the risk of low birth weight or preterm delivery: Benefits of cessation and tobacco control policies Tobacco Induced Diseases, 2023/05/29. Michel-Henri Delcroix, Conchita Delcroix-Gomez, Pierre Marquet, Tristan Gauthier, Daniel Thomas, Yves Aubard. DOI 10.18332/tid/156854
Posttranslational-modifications of human-serum-albumin analysis by a top-down approach validated by a comprehensive bottom-up analysis Journal of Chromatography B, 2023/05. Mohamad-Ali Rahali, Roy Lakis, François-Ludovic Sauvage, Emilie Pinault, Pierre Marquet, Franck Saint-Marcoux, Souleiman El Balkhi. DOI 10.1016/j.jchromb.2023.123740
New perspectives for the therapeutic drug monitoring of tacrolimus: Quantification in volumetric DBS based on an automated extraction and LC-MS/MS analysis. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2023/04. Rosé G, Tafzi N, El Balkhi S, Rerolle JP, Debette-Gratien M, Marquet P, Saint-Marcoux F, Monchaud C. DOI 10.1016/j.jchromb.2023.123721
Modulation of Monocyte Response by MicroRNA-15b/106a/374a During Antibody-mediated Rejection in Kidney Transplantation. Transplantation, 2023/04. Tinel C, Lamarthée B, Gazut S, Van Loon E, Von Tokarski F, Benon A, Sauvaget V, Garcia-Paredes V, Ménager M, Morin L, Aouni L, Cagnard N, Rabant M, Anglicheau D. DOI 10.1097/tp.0000000000004393
Does the Tacrolimus Trough Level Adequately Predict Drug Exposure in Patients Requiring a High Tacrolimus Dose? Transplantation direct, 2023/03. Haverals L, Roosens L, Wouters K, Marquet P, Monchaud C, Massart A, Abramowicz D, Hellemans R. DOI 10.1097/txd.0000000000001439
A Hybrid Algorithm Combining Population Pharmacokinetic and Machine Learning for Isavuconazole Exposure Prediction. Pharmaceutical research, 2023/03. Destere A, Marquet P, Labriffe M, Drici MD, Woillard JB. DOI 10.1007/s11095-023-03507-y
Mycophenolate Mofetil Dose Adjustment in Pediatric Kidney Transplant Recipients. Therapeutic drug monitoring, 2023/02. Labriffe M, Micallef L, Woillard JB, Monchaud C, Saint-Marcoux F, Debord J, Marquet P. DOI 10.1097/ftd.0000000000001087
Longitudinal Exposure to Tacrolimus and New-Onset Diabetes Mellitus in Renal Transplant Patients. Therapeutic drug monitoring, 2023/02. Destere A, Premaud A, Monchaud C, Marquet P, Woillard JB. DOI 10.1097/ftd.0000000000001035
[History of pharmacology-toxicology in Limoges]. Therapie, 2023/02. Marquet P, Laroche ML, Merle L, Lachâtre G, au nom de la pharmacologie-toxicologie Limousine. DOI 10.1016/j.therap.2023.02.003
Ultrafast Measurement of Metformin in the Clinical Setting Using Probe Electrospray Ionization Mass Spectrometry. Journal of analytical toxicology, 2023/02. Griffeuille P, El Balkhi S, Bodeau S, Lamoureux F, Marquet P, Dulaurent S, Saint-Marcoux F. DOI 10.1093/jat/bkac034
Substrate binding and lipid-mediated allostery in the human organic anion transporter 1 at the atomic-scale. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023/02. Janaszkiewicz A, Tóth Á, Faucher Q, Arnion H, Védrenne N, Barin-Le Guellec C, Marquet P, Di Meo F. DOI 10.1016/j.biopha.2023.114342
Application of machine learning to predict tacrolimus exposure in liver and kidney transplant patients given the MeltDose formulation. European journal of clinical pharmacology, 2022/12. Ponthier L, Marquet P, Moes DJAR, Rostaing L, van Hoek B, Monchaud C, Labriffe M, Woillard JB. DOI 10.1007/s00228-022-03445-5
Can the Area Under the Curve/Trough Level Ratio Be Used to Optimize Tacrolimus Individual Dose Adjustment? Transplantation, 2022/11. Woillard JB, Monchaud C, Saint-Marcoux F, Labriffe M, Marquet P. DOI 10.1097/tp.0000000000004405
Fetal growth restriction, low birth weight, and preterm birth: Effects of active or passive smoking evaluated by maternal expired CO at delivery, impacts of cessation at different trimesters Tobacco Induced Diseases, 2022/08/26. Conchita Delcroix-Gomez, Michel-Henri Delcroix, Amal Jamee, Tristan Gauthier, Pierre Marquet, Yves Aubard. DOI 10.18332/tid/152111
Uterine Factor Infertility, a Systematic Review. Journal of clinical medicine, 2022/08. Sallée C, Margueritte F, Marquet P, Piver P, Aubard Y, Lavoué V, Dion L, Gauthier T. DOI 10.3390/jcm11164907
Pharmacokinetics, Pharmacodynamics, and Therapeutic Drug Monitoring of Valganciclovir and Ganciclovir in Transplantation Clinical Pharmacology & Therapeutics, 2022/08. Bénédicte Franck, Julie Autmizguine, Pierre Marquet, Philippe Ovetchkine, Jean‐Baptiste Woillard. DOI 10.1002/cpt.2431
Optimization of Vancomycin Initial Dose in Term and Preterm Neonates by Machine Learning. Pharmaceutical research, 2022/08. Ponthier L, Ensuque P, Destere A, Marquet P, Labriffe M, Jacqz-Aigrain E, Woillard JB. DOI 10.1007/s11095-022-03351-6
Machine learning algorithms to estimate everolimus exposure trained on simulated and patient pharmacokinetic profiles CPT: Pharmacometrics & Systems Pharmacology, 2022/08. Marc Labriffe, Jean‐Baptiste Woillard, Jean Debord, Pierre Marquet. DOI 10.1002/psp4.12810
Substrate binding and lipid-mediated allostery in the human organic anion transporter 1 at the atomic-scale 2022/07/15. Angelika Janaszkiewicz, Ágota Tóth, Quentin Faucher, Hélène Arnion, Nicolas Védrenne, Chantal Barin-Le Guellec, Pierre Marquet, Florent Di Meo. DOI 10.1101/2022.07.14.500056
Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII+ innate immune cells in rejection 2022/07. Lamarthée B, Callemeyn J, Herck YV, Antoranz A, Anglicheau D, Becker JU, Debyser T, Smet FD, Vusser KD, Eloudzeri M, Franken A, Gwinner W, Koshy P, Naesens M. DOI 10.1101/2022.07.07.22276374
Is Intestinal Dysbiosis-Associated With Immunosuppressive Therapy a Key Factor in the Pathophysiology of Post-Transplant Diabetes Mellitus? Frontiers in endocrinology, 2022/07. Faucher Q, Jardou M, Brossier C, Picard N, Marquet P, Lawson R. DOI 10.3389/fendo.2022.898878
Population pharmacokinetics and Bayesian estimation of mycophenolate mofetil in patients with autoimmune hepatitis. British journal of clinical pharmacology, 2022/05. Nanga TM, Woillard JB, Rousseau A, Marquet P, Prémaud A. DOI 10.1111/bcp.15389
Biological pathways and comparison with biopsy signals and cellular origin of peripheral blood transcriptomic profiles during kidney allograft pathology. Kidney international, 2022/05. Van Loon E, Lamarthée B, de Loor H, Van Craenenbroeck AH, Brouard S, Danger R, Giral M, Callemeyn J, Tinel C, Cortés Calabuig Á, Koshy P, Naesens M. DOI 10.1016/j.kint.2022.03.026
A Hybrid Model Associating Population Pharmacokinetics with Machine Learning: A Case Study with Iohexol Clearance Estimation. Clinical pharmacokinetics, 2022/05. Destere A, Marquet P, Gandonnière CS, Åsberg A, Loustaud-Ratti V, Carrier P, Ehrmann S, Guellec CB, Premaud A, Woillard JB. DOI 10.1007/s40262-022-01138-x
Perfusate Metabolomics Content and Expression of Tubular Transporters During Human Kidney Graft Preservation by Hypothermic Machine Perfusion. Transplantation, 2022/04. Faucher Q, Alarcan H, Sauvage FL, Forestier L, Miquelestorena-Standley E, Nadal-Desbarats L, Arnion H, Venhard JC, Brichart N, Bruyère F, Marquet P, Barin-Le Guellec C. DOI 10.1097/tp.0000000000004129
Noninvasive Diagnosis of Acute Rejection in Renal Transplant Patients Using Mass Spectrometric Analysis of Urine Samples: A Multicenter Diagnostic Phase III Trial. Transplantation direct, 2022/04. Gwinner W, Karch A, Braesen JH, Khalifa AA, Metzger J, Naesens M, Van Loon E, Anglicheau D, Marquet P, Budde K, Matz M, Arns W, Fischereder M, Koch A. DOI 10.1097/txd.0000000000001316
Insights into the structure and function of the human organic anion transporter 1 in lipid bilayer membranes. Scientific reports, 2022/04. Janaszkiewicz A, Tóth Á, Faucher Q, Martin M, Chantemargue B, Barin-Le Guellec C, Marquet P, Di Meo F. DOI 10.1038/s41598-022-10755-2
A Machine Learning Approach to Predict Interdose Vancomycin Exposure. Pharmaceutical research, 2022/04. Bououda M, Uster DW, Sidorov E, Labriffe M, Marquet P, Wicha SG, Woillard JB. DOI 10.1007/s11095-022-03252-8
Urinary collagen-derived peptides as sensitive markers for bone resorption and bisphosphonate treatment in kidney transplant patients 2022/02. Marx D, Anglicheau D, Caillard S, Moulin B, Kochman A, Mischak H, Pejchinowski M, Latosinska A, Bienaimé F, Prié D, Marquet P, Perrin P, Gwinner W, Metzger J. DOI 10.1101/2022.02.15.22270979
Insights into the structure and function of the human organic anion transporter 1 in lipid bilayer membranes 2022/01/12. Angelika Janaszkiewicz, Ágota Tóth, Quentin Faucher, Marving Martin, Benjamin Chantemargue, Chantal Barin-Le Guellec, Pierre Marquet, Florent Di Meo. DOI 10.1101/2022.01.10.475390
Metabolic interactions of benzodiazepines with oxycodone ex vivo and toxicity depending on usage patterns in an animal model. British journal of pharmacology, 2022/01. Lawson R, Čechová P, Zarrouk E, Javellaud J, Bazgier V, Otyepka M, Trouillas P, Picard N, Marquet P, Saint-Marcoux F, El Balkhi S. DOI 10.1111/bph.15765
How has the future investment program stimulated research and innovation in health? Therapie, 2022/01. Bordet R, Dantonel JC, Vacaresse E, Le Jeunne C, Benhabiles N, Beretz A, Boitard C, Debette S, Duluc G, Froguel P, Garbil B, Lyonnet S, Mahfoudi A, Zins M. DOI 10.1016/j.therap.2022.01.009
Comment le programme d’investissements d’avenir a-t-il stimulé la recherche et l’innovation en santé ? Therapie, 2022/01. Bordet R, Dantonel JC, Vacaresse E, Le Jeunne C, Benhabiles N, Beretz A, Boitard C, Debette S, Duluc G, Froguel P, Garbil B, Lyonnet S, Mahfoudi A, Zins M. DOI 10.1016/j.therap.2022.01.005
A single Bayesian estimator for iohexol clearance estimation in ICU, liver failure and renal transplant patients. British journal of clinical pharmacology, 2022/01. Destere A, Salmon Gandonnière C, Åsberg A, Loustaud-Ratti V, Carrier P, Ehrmann S, Barin-Le Guellec C, Marquet P, Woillard JB. DOI 10.1111/bcp.15197
Therapeutic Drug Monitoring in the Era of Precision Medicine: Achievements, Gaps, and Perspectives-An Interview in Honor of Professor Charles Pippenger. Therapeutic drug monitoring, 2021/12. Wong SH, Marquet P, Cattaneo D, Svinarov D, Bergan S, Walson P, Vinks AA, Shipkova M. DOI 10.1097/ftd.0000000000000932
Population Pharmacokinetics And Bayesian Estimation of Mycophenolate Mofetil In Patients With Autoimmune Hepatitis 2021/11. Nanga T, Woillard J, Rousseau A, Marquet P, Prémaud A. DOI 10.22541/au.163577198.80163436/v1
Integrative Omics Analysis Unravels Microvascular Inflammation-Related Pathways in Kidney Allograft Biopsies. Frontiers in immunology, 2021/11. Tinel C, Lamarthée B, Callemeyn J, Van Loon E, Sauvaget V, Morin L, Aouni L, Rabant M, Gwinner W, Marquet P, Naesens M, Anglicheau D. DOI 10.3389/fimmu.2021.738795
Therapeutic education as a tool to improve patient-reported and clinical outcomes after renal transplantation: results of the EPHEGREN multicenter retrospective cohort study. Transplant international : official journal of the European Society for Organ Transplantation, 2021/10. Villeneuve C, Rerolle JP, Couzi L, Westeel PF, Etienne I, Esposito L, Kamar N, Büchler M, Thierry A, Marquet P, Monchaud C. DOI 10.1111/tri.14127
Machine learning-supported interpretation of kidney graft elementary lesions in combination with clinical data 2021/09/22. Marc Labriffe, Jean-Baptiste Woillard, Wilfried Gwinner, Jan-Hinrich Braesen, Dany Anglicheau, Marion Rabant, Priyanka Koshy, Maarten Naesens, Pierre Marquet. DOI 10.1101/2021.09.17.21263552
Perfusate metabolomics content and tubular transporters expression during kidney graft preservation by hypothermic machine perfusion 2021/09. Faucher Q, Alarcan H, Sauvage F, Forestier L, Miquelestorena-Standley E, Nadal-Desbarats L, Arnion H, Venhard J, Brichart N, Bruyère F, Marquet P, Guellec CB. DOI 10.1101/2021.09.27.21264167
Multi-omics investigation of tacrolimus nephrotoxicity 2021/07. Aouad H, Faucher Q, Sauvage F, Pinault E, Barrot C, Arnion H, Marquet P, Essig M. DOI 10.1101/2021.07.29.454229
Thoroughly Validated Bayesian Estimator and Limited Sampling Strategy for Dose Individualization of Ganciclovir and Valganciclovir in Pediatric Transplant Recipients. Clinical pharmacokinetics, 2021/05/29. DOI 10.1007/s40262-021-01034-w
Clinical Pharmacokinetics and Bayesian Estimators for the Individual Dose Adjustment of a Generic Formulation of Tacrolimus in Adult Kidney Transplant Recipients Clinical Pharmacokinetics, 2021/05/24. Pierre Marquet, Alexandre Destère, Caroline Monchaud, Jean-Philippe Rérolle, Matthias Buchler, Hakim Mazouz, Isabelle Etienne, Antoine Thierry, Nicolas Picard, Jean-Baptiste Woillard, Jean Debord. DOI 10.1007/s40262-020-00959-y
High-throughput sequencing defines donor and recipient HLA B-cell epitope frequencies for prospective matching in transplantation. Communications biology, 2021/05/14. DOI 10.1038/s42003-021-01989-3
Towards therapeutic drug monitoring of mycophenolic acid in mucous membrane pemphigoid: A retrospective single-centre study. Fundamental & clinical pharmacology, 2021/04/29. DOI 10.1111/fcp.12688
Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology. Therapeutic drug monitoring, 2021/04/01. DOI 10.1097/ftd.0000000000000871
Estimation of drug exposure by machine learning based on simulations from published pharmacokinetic models: The example of tacrolimus. Pharmacological research, 2021/03/26. DOI 10.1016/j.phrs.2021.105578
First-Line Toxicological Screening with Fully Automated Extraction. Journal of analytical toxicology, 2021/03/01. DOI 10.1093/jat/bkaa075
Mycophenolic acid exposure prediction using machine learning. Clinical pharmacology and therapeutics, 2021/02/24. DOI 10.1002/cpt.2216
A Machine Learning Approach to Estimate the Glomerular Filtration Rate in Intensive Care Unit Patients Based on Plasma Iohexol Concentrations and Covariates. Clinical pharmacokinetics, 2021/02/01. DOI 10.1007/s40262-020-00927-6
Population pharmacokinetics of ganciclovir and valganciclovir in paediatric solid organ and stem cell transplant recipients. British journal of clinical pharmacology, 2020/12/29. DOI 10.1111/bcp.14719
A Population Pharmacokinetic Modeling Approach to Determine the Efficacy of Intravenous Amikacin in Children with Cystic Fibrosis. Therapeutic drug monitoring, 2020/12/17. DOI 10.1097/ftd.0000000000000855
Immunosuppressant quantification in intravenous microdialysate - towards novel quasi-continuous therapeutic drug monitoring in transplanted patients. Clinical chemistry and laboratory medicine, 2020/12/15. DOI 10.1515/cclm-2020-1542
Analyses of AUC(0-12) and C0 Compliances within Therapeutic Ranges in Kidney Recipients Receiving Cyclosporine or Tacrolimus. Journal of clinical medicine, 2020/12/01. DOI 10.3390/jcm9123903
Tacrolimus Exposure Prediction Using Machine Learning. Clinical pharmacology and therapeutics, 2020/11/30. DOI 10.1002/cpt.2123
The scientific basis of rational prescribing. A guide to precision clinical pharmacology based on the WHO 6-step method. European journal of clinical pharmacology, 2020/11/18. DOI 10.1007/s00228-020-03044-2
Tacrolimus Bayesian dose adjustment in pediatric renal transplant recipients. Therapeutic drug monitoring, 2020/10/30. DOI 10.1097/ftd.0000000000000828
MRP4 is responsible for the efflux transport of mycophenolic acid β-d glucuronide (MPAG) from hepatocytes to blood. Xenobiotica; the fate of foreign compounds in biological systems, 2020/09/06. DOI 10.1080/00498254.2020.1813352
Effects of Ischemia-Reperfusion on Tubular Cell Membrane Transporters and Consequences in Kidney Transplantation. Journal of clinical medicine, 2020/08/12. DOI 10.3390/jcm9082610
Phenotyping of Uracil and 5-Fluorouracil Metabolism Using LC-MS/MS for Prevention of Toxicity and Dose Adjustment of Fluoropyrimidines. Therapeutic drug monitoring, 2020/08/01. DOI 10.1097/ftd.0000000000000768
Antibody-mediated rejection with and without donor-specific anti-human leucocyte antigen antibodies: performance of the peripheral blood 8-gene expression assay. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2020/08/01. DOI 10.1093/ndt/gfaa096
Transcriptional Changes in Kidney Allografts with Histology of Antibody-Mediated Rejection without Anti-HLA Donor-Specific Antibodies. Journal of the American Society of Nephrology : JASN, 2020/07/08. DOI 10.1681/asn.2020030306
Urinary Protein Biomarker Panel for the Diagnosis of Antibody-Mediated Rejection in Kidney Transplant Recipients. Kidney international reports, 2020/06/29. DOI 10.1016/j.ekir.2020.06.018
Evaluation of Longitudinal Exposure to Tacrolimus as a Risk Factor of Chronic Kidney Disease Occurrence Within the First Year Post-Liver Transplantation. Transplantation, 2020/06/29. DOI 10.1097/tp.0000000000003384
Development and validation of an optimized integrative model using urinary chemokines for noninvasive diagnosis of acute allograft rejection. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020/06/27. DOI 10.1111/ajt.15959
[Summary of the recommendations of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) on the therapeutic drug monitoring of tacrolimus]. Therapie, 2020/06/20. DOI 10.1016/j.therap.2020.06.004
Real life experience of mycophenolate mofetil monotherapy in liver transplant patients. Clinics and research in hepatology and gastroenterology, 2020/06/11. DOI 10.1016/j.clinre.2020.04.017
Professor Folke Sjöqvist peacefully passed away on March 30, 2020. European journal of clinical pharmacology, 2020/06/10. DOI 10.1007/s00228-020-02911-2
The FcγRIIIA-158 VV genotype increased the risk of post-transplant lymphoproliferative disorder in T-cell-depleted kidney transplant recipients - a retrospective study. Transplant international : official journal of the European Society for Organ Transplantation, 2020/05/14. DOI 10.1111/tri.13624
Population pharmacokinetics of gentamicin in haemodialysis patients: modelling, simulations and recommendations. European journal of clinical pharmacology, 2020/05/01. DOI 10.1007/s00228-020-02867-3
Pharmacokinetic evaluation of MFF in combinations with tacrolimus and cyclosporine. Findings of C0 and AUC. Medicine, 2020/03/01. DOI 10.1097/md.0000000000019441
Population pharmacokinetics and Bayesian estimators for intravenous mycophenolate mofetil in haematopoietic stem cell transplant patients. British journal of clinical pharmacology, 2020/02/28. DOI 10.1111/bcp.14261
Automatic quantification of uracil and dihydrouracil in plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020/02/21. DOI 10.1016/j.jchromb.2020.122038
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