Répertoire du corps professoral

Urethral reconstruction using tissue engineering, final steps towards clinical translation
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 octobre 2024 au 31 mars 2025

Tissue-Targeted Scaffolds: Integrating Tissue-Specific Biological Cues to Enhance Bioactivity
Programme: Subventions à la découverte SD (individuelles et d'équipe)
Organisme(s) subventionnaire(s): Conseil de recherches en sciences naturelles et génie Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2024 au 31 mars 2029

Alternum optimization and validation to support primary cell growth, an in depth study of cell metabolism and signalling
Programme: Accélération Québec (MITACS et gouvernement provincial)
Organisme(s) subventionnaire(s): MITACS Inc.
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 avril 2024 au 31 octobre 2025

Urogenital tissue engineering solutions for transgender surgeries
Programme: Fonds Nouvelles frontières en recherche - Volet Exploration
Organisme(s) subventionnaire(s): Secrétariat des programmes interorganismes à l’intention des établissements
Type de financement: Subvention
Établissement tête: Université Laval
Du 31 mars 2024 au 30 mars 2026

Un environnement sécuritaire pour des animaux immunosupprimés
Programme: Fonds des leaders John-R.-Evans (FLJR)
Organisme(s) subventionnaire(s): Fondation Canadienne pour l'innovation (La), Centre hospitalier universitaire de Québec - Université Laval, Ministère de la Santé et des Services sociaux
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 janvier 2023 au 31 mars 2025

Projet exploratoire où nous voulons introduire des matrices conçues par électrospinning dans nos projets de génies tissulaires urologiques
Programme: Développement de la recherche (FC)
Organisme(s) subventionnaire(s): CHU de Québec – Université Laval – CHUL
Type de financement: Subvention
Établissement tête: Université Laval
Du 15 septembre 2022 au 31 décembre 2024

Tissue-engineered solutions for uro-genital reconstruction, and replacing banned synthetic meshes
Programme: Subvention Projet
Organisme(s) subventionnaire(s): Instituts de recherche en santé du Canada
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 octobre 2021 au 30 septembre 2026

Financements des 2 dernières années

Alternum optimization and validation to support primary cell growth and advanced 3D model
Programme: Accélération Québec (MITACS et gouvernement provincial)
Organisme(s) subventionnaire(s): MITACS Inc.
Type de financement: Subvention
Établissement tête: Université Laval
Du 15 janvier 2024 au 30 août 2024

Bisphenol-inducted stromal compartment modifications in bladder cancer using a 3D
Organisme(s) subventionnaire(s): Association canadienne d'urologie
Type de financement: Subvention
Établissement tête: Université Laval
Du 1 mai 2023 au 30 avril 2024

SOUTIEN AUX ÉTABLISSEMENTS POUR L'IMPLANTATION D'OUTILS COMMUNS EN RECHERCHE CLINIQUE ET POUR LA MISE EN ŒUVRE DU SERVICE D'ÉVALUATION ACCÉLÉRÉE
Organisme(s) subventionnaire(s): Catalis
Type de financement: Subvention
Établissement tête: Université Laval
Du 23 février 2022 au 30 juin 2024

Génie tissulaire urologique
Organisme(s) subventionnaire(s): Fondation du CHU de Québec
Type de financement: Subvention
Établissement tête: Université Laval
Du 12 mars 2019 au 11 mars 2023

Alexandre Zidat, Maîtrise en génie mécanique - avec mémoire

Félix-Antoine Pellerin, Maîtrise en sciences cliniques et biomédicales - avec mémoire

Elissa Elia, Doctorat en biologie cellulaire et moléculaire

Saeed Farzamfar, Stage postdoctoral en médecine

David Brownell, Doctorat en biologie cellulaire et moléculaire

Megan Richer, Maîtrise en sciences cliniques et biomédicales - avec mémoire

Encadrements terminés dans les 5 dernières années

Devi Paramitha, Maîtrise en génie des matériaux et de la métallurgie - avec mémoire

Eve Pellerin, Maîtrise en sciences cliniques et biomédicales - avec mémoire

Weronika Jakubowska, Maîtrise en médecine expérimentale - avec mémoire

Amélie Morissette, Maîtrise en biologie cellulaire et moléculaire - avec mémoire

Cassandra Ringuette Goulet, Doctorat en biologie cellulaire et moléculaire

Sara Bouhout, Doctorat en biologie cellulaire et moléculaire

Maxime Tondreau, Doctorat en biologie cellulaire et moléculaire

Publications des 5 dernières années

Mimicking Urinary Tract Infections Caused by Uropathogenic Escherichia coli Using a Human Three-Dimensional Tissue Engineering Model Microorganisms, 2024/10/26. Félix-Antoine Pellerin, Élodie Dufresne, Stéphane Chabaud, Hazem Orabi, Stéphane Bolduc. DOI 10.3390/microorganisms12112155

Epithelia of the Penile Urethra 2024/10/01. Matisse Duval, David Brownell, Stéphane Chabaud, Alexis Laungani, Eric Philippe, Stephane Bolduc. DOI 10.20944/preprints202410.0042.v1

Navigating the Immunological Crossroads: Mesenchymal Stem/Stromal Cells as Architects of Inflammatory Harmony in Tissue-Engineered Constructs Bioengineering, 2024/05/16. Saeed Farzamfar, Luciana Garcia, Mahya Rahmani, Stephane Bolduc. DOI 10.3390/bioengineering11050494

Tissue Engineering for Penile Reconstruction Bioengineering, 2024/02/28. Elissa Elia, Christophe Caneparo, Catherine McMartin, Stéphane Chabaud, Stéphane Bolduc. DOI 10.3390/bioengineering11030230

Biological Macromolecule-Based Scaffolds for Urethra Reconstruction Biomolecules, 2023/07/26. Saeed Farzamfar, Megan Richer, Mahya Rahmani, Mohammad Naji, Mehdi Aleahmad, Stéphane Chabaud, Stéphane Bolduc. DOI 10.3390/biom13081167

Extracellular Matrix-Based and Electrospun Scaffolding Systems for Vaginal Reconstruction Bioengineering, 2023/07/01. Saeed Farzamfar, Elissa Elia, Megan Richer, Stéphane Chabaud, Mohammad Naji, Stéphane Bolduc. DOI 10.3390/bioengineering10070790

Tissue Engineering for Gastrointestinal and Genitourinary Tracts International Journal of Molecular Sciences, 2022/12/20. Elissa Elia, David Brownell, Stéphane Chabaud, Stéphane Bolduc. DOI 10.3390/ijms24010009

Tissue Engineering for Gastrointestinal and Genitourinary Tracts 2022/11/15. Elissa Elia, David Brownell, Stéphane Chabaud, Stéphane Bolduc. DOI 10.20944/preprints202211.0261.v1

UPEC Colonic-Virulence and Urovirulence Are Blunted by Proanthocyanidins-Rich Cranberry Extract Microbial Metabolites in a Gut Model and a 3D Tissue-Engineered Urothelium Microbiology spectrum, 2022. DOI 10.1128/spectrum.02432-21

Tissue Engineering in Gynecology 2022. DOI 10.20944/preprints202209.0132.v1

Tissue Engineering in Gynecology International journal of molecular sciences, 2022. DOI 10.3390/ijms232012319

Prospects and Challenges of Electrospun Cell and Drug Delivery Vehicles to Correct Urethral Stricture International journal of molecular sciences, 2022. DOI 10.3390/ijms231810519

Perception and satisfaction of patients after telemedicine urology consultations: A matched analysis with physicians' perspective Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2022. DOI 10.5489/cuaj.7819

Glucuronidated Metabolites of Bisphenols A and S Alter the Properties of Normal Urothelial and Bladder Cancer Cells International journal of molecular sciences, 2022. DOI 10.3390/ijms232112859

First North American experience of propiverine use in children with overactive bladder Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2022. DOI 10.5489/cuaj.7811

Evaluation of a Serum-Free Medium for Human Epithelial and Stromal Cell Culture International journal of molecular sciences, 2022. DOI 10.3390/ijms231710035

Comprehensive overview of the available pharmacotherapy for the treatment of non-neurogenic overactive bladder in children Expert opinion on pharmacotherapy, 2022. DOI 10.1080/14656566.2022.2072212

Cancer-Associated Fibroblasts in a 3D Engineered Tissue Model Induce Tumor-like Matrix Stiffening and EMT Transition Cancers, 2022. DOI 10.3390/cancers14153810

Bladder cancer cell lines adapt their aggressiveness profile to oxygen tension Oncology letters, 2022. DOI 10.3892/ol.2022.13341

Bisphenols A and S Alter the Bioenergetics and Behaviours of Normal Urothelial and Bladder Cancer Cells Cancers, 2022. DOI 10.3390/cancers14164011

Reconstruction of Vascular and Urologic Tubular Grafts by Tissue Engineering Processes, 2021/03/12. Christophe Caneparo, Stéphane Chabaud, Stéphane Bolduc. DOI 10.3390/pr9030513

Immunocompetent Human 3D Organ-Specific Hormone-Responding Vaginal Mucosa Model of HIV-1 Infection Tissue engineering. Part C, Methods, 2021. DOI 10.1089/ten.tec.2020.0333

Heat-Inactivation of Fetal and Newborn Sera Did Not Impair the Expansion and Scaffold Engineering Potentials of Fibroblasts Bioengineering (Basel, Switzerland), 2021. DOI 10.3390/bioengineering8110184

Genitourinary Tissue Engineering: Reconstruction and Research Models Bioengineering (Basel, Switzerland), 2021. DOI 10.3390/bioengineering8070099

Endocrine-disrupting effects of bisphenols on urological cancers Environmental research, 2021. DOI 10.1016/j.envres.2020.110485

Considerations for the clinical use of stem cells in genitourinary regenerative medicine World journal of stem cells, 2021. DOI 10.4252/wjsc.v13.i10.1480

Case - Bilateral and recurrent pediatric cystic nephroma associated with DICER1 mutation Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2021. DOI 10.5489/cuaj.6836

Bisphenol A Alters the Energy Metabolism of Stromal Cells and Could Promote Bladder Cancer Progression Cancers, 2021. DOI 10.3390/cancers13215461

Use of a magnetic double J stent in pediatric patients: A case-control study at two Canadian pediatric centers Journal of pediatric surgery, 2020. DOI 10.1016/j.jpedsurg.2019.03.014

Prioritization and management recommendations of pediatric urology conditions during the COVID-19 pandemic Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2020. DOI 10.5489/cuaj.6693

Prevascularized Tissue-Engineered Human Vaginal Mucosa: <i>In Vitro</i> Optimization and <i>In Vivo</i> Validation Tissue engineering. Part A, 2020. DOI 10.1089/ten.tea.2020.0036

Innovative Human Three-Dimensional Tissue-Engineered Models as an Alternative to Animal Testing Bioengineering (Basel, Switzerland), 2020. DOI 10.3390/bioengineering7030115

Human Organ-Specific 3D Cancer Models Produced by the Stromal Self-Assembly Method of Tissue Engineering for the Study of Solid Tumors BioMed research international, 2020. DOI 10.1155/2020/6051210

Conditioned medium produced by fibroblasts cultured in low oxygen pressure allows the formation of highly structured capillary-like networks in fibrin gels Scientific reports, 2020. DOI 10.1038/s41598-020-66145-z

Case - Confirmed testicular mass on ultrasound with no evidence on histology in two teenagers Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2020. DOI 10.5489/cuaj.6083

A randomized, crossover trial comparing the efficacy and safety of fesoterodine and extended-release oxybutynin in children with overactive bladder with 12-month extension on fesoterodine: The FOXY study Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2020. DOI 10.5489/cuaj.6247

A prospective, multisite study analyzing the percentage of urological cases that can be completely managed by telemedicine Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2020. DOI 10.5489/cuaj.6862

Evaluating the distance travelled for urological pediatric appointments Canadian Urological Association journal = Journal de l'Association des urologues du Canada, 2019. DOI 10.5489/cuaj.5892

Collagen hollow structure for bladder tissue engineering Materials science & engineering. C, Materials for biological applications, 2019. DOI 10.1016/j.msec.2019.04.052

Cancer-associated fibroblasts induce epithelial-mesenchymal transition of bladder cancer cells through paracrine IL-6 signalling BMC cancer, 2019. DOI 10.1186/s12885-019-5353-6

Biological Assessment of Zn-Based Absorbable Metals for Ureteral Stent Applications Materials (Basel, Switzerland), 2019. DOI 10.3390/ma12203325